Portugal were criticised following a 1-1 draw against DR Congo in their opening game of the tournament.
They doubled their lead in the 17th minute in Houston with Nuno Mendes scoring directly with a low free-kick.
Uzbekistan thought they Equalized as Aziz shot into the net, but the effort was ruled out because Cancelo was fouled.
“Lionel Messi became the World Cup’s all-time leading scorer with 18 goals but failed to score in the 2010 tournament.”
Ronaldo has now struck 10 times, having scored once at the 2006, 2010, 2014 and 2022 finals and four times in 2018, including a hat-trick in a 3-3 draw with Spain.
Under pressure and scrutiny, Ronaldo responded to the doubters, taking six minutes to make his mark on Tuesday.
His delight at scoring was obvious, ending an 11-game goal drought at a World Cup or European Championship.
He almost scored a first-hat-trick with an innovative lofted strike, only for Manchester City defender Abdukodir Khusanov to clear the ball off the line.
Portugal chased a Ronaldo hat-trick, but Rafael Leao sealed the victory with a powerful late strike.
At full-time, a delighted Ronaldo was seen shouting “I’m back, I’m back” into the camera. His double, and a place in the record books, certainly proved that.